Self-taught, George Mgrdichian has been credited with taking the oud from the cabaret to the concert stage. He has a broad repertoire that includes classical, folk, and popular music from many cultures, as well as his own compositions. He has appeared extensively at colleges, universities, and major concert halls throughout the United States and Europe. He holds Bachelor of Music and Master of Science degrees from the Juilliard School of Music and has complete doctoral studies at Wesleyan University in Middletown, Connecticut. His debut recital took place at the University of Pennsylvania in Philadelphia. His 1967 New York City debut recital at Town Hall was followed by an invitation to appear as guest artist on a program with the New York Philharmonic, an event which marked the first appearance of the oud with a major symphony orchestra.
George Mgrdichian's performances have taken him to Avery Fisher Hall, Carnegie Hall, Alice Tully Hall, Wolf Trap, Felt Forum, Kennedy Center and the Academy of Music in Philadelphia, as well as colleges and universities throughout the United States. His European debut, which was heralded by the critics, took place in Stockholm through an invitation to perform at the Stockholm Music Festival. His artistry can be heard on over 65 recordings, including "The New Sounds of the Middle East" which received Special Merit Awards from Stereo Review and Billboard magazines. He has performed on recordings with David Amram (RCA Victor), Phil Woods (ABC), the Waverly Consort (CBS Masterworks and Vanguard), and The Gerard Edery Ensemble (Sefarad Records). The winner of many awards and accolades, George Mgrdichian has composed and performed with numerous recording ensembles for motion picture and television soundtracks.